Detalhe da pesquisa
1.
Histone H3.3 K27M and K36M mutations de-repress transposable elements through perturbation of antagonistic chromatin marks.
Mol Cell
; 81(23): 4876-4890.e7, 2021 12 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34739871
2.
Targeting placental growth factor/neuropilin 1 pathway inhibits growth and spread of medulloblastoma.
Cell
; 152(5): 1065-76, 2013 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-23452854
3.
The molecular landscape of ETMR at diagnosis and relapse.
Nature
; 576(7786): 274-280, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31802000
4.
Germline pathogenic SMARCA4 variants in neuroblastoma.
J Med Genet
; 60(10): 987-992, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36813544
5.
SWI/SNF-deficient tumors of the central nervous system: An update.
Clin Neuropathol
; 43(1): 2-9, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-37969088
6.
Rhabdoid tumors in patients conceived following ART: is there an association?
Hum Reprod
; 38(10): 2028-2038, 2023 Oct 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37553222
7.
Recurrent atypical teratoid/rhabdoid tumors (AT/RT) reveal discrete features of progression on histology, epigenetics, copy number profiling, and transcriptomics.
Acta Neuropathol
; 146(3): 527-541, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37450044
8.
Update on quality assurance in neuropathology: Summary of the round robin trials on TERT promoter mutation, H3-3A mutation, 1p/19q codeletion, and KIAA1549::BRAF fusion testing in Germany in 2020 and 2021.
Clin Neuropathol
; 42(3): 112-121, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36999511
9.
Spatial molecular profiling of a central nervous system low-grade diffusely infiltrative tumour with INI1 deficiency featuring a high-grade atypical teratoid/rhabdoid tumour component.
Neuropathol Appl Neurobiol
; 48(3): e12777, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34820878
10.
Low-grade diffusely infiltrative tumour (LGDIT), SMARCB1-mutant: A clinical and histopathological distinct entity showing epigenetic similarity with ATRT-MYC.
Neuropathol Appl Neurobiol
; 48(4): e12797, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35152461
11.
ATRT-SHH comprises three molecular subgroups with characteristic clinical and histopathological features and prognostic significance.
Acta Neuropathol
; 143(6): 697-711, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35501487
12.
Transposable element insertion as a mechanism of SMARCB1 inactivation in atypical teratoid/rhabdoid tumor.
Genes Chromosomes Cancer
; 60(8): 586-590, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33896072
13.
Inhibition of nuclear export restores nuclear localization and residual tumor suppressor function of truncated SMARCB1/INI1 protein in a molecular subset of atypical teratoid/rhabdoid tumors.
Acta Neuropathol
; 142(2): 361-374, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34003336
14.
Atypical teratoid/rhabdoid tumors (ATRTs) with SMARCA4 mutation are molecularly distinct from SMARCB1-deficient cases.
Acta Neuropathol
; 141(2): 291-301, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33331994
15.
Genetic and epigenetic characterization of posterior pituitary tumors.
Acta Neuropathol
; 142(6): 1025-1043, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34661724
16.
TERT promoter mutation and chromosome 6 loss define a high-risk subtype of ependymoma evolving from posterior fossa subependymoma.
Acta Neuropathol
; 141(6): 959-970, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33755803
17.
Primary mismatch repair deficient IDH-mutant astrocytoma (PMMRDIA) is a distinct type with a poor prognosis.
Acta Neuropathol
; 141(1): 85-100, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33216206
18.
Clear cell meningiomas are defined by a highly distinct DNA methylation profile and mutations in SMARCE1.
Acta Neuropathol
; 141(2): 281-290, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33319313
19.
Glioblastomas with primitive neuronal component harbor a distinct methylation and copy-number profile with inactivation of TP53, PTEN, and RB1.
Acta Neuropathol
; 142(1): 179-189, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33876327
20.
Clinical evidence for a biological effect of epigenetically active decitabine in relapsed or progressive rhabdoid tumors.
Pediatr Blood Cancer
; 68(12): e29267, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34347371